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Venkatanarayanan, V.
- Evaluation of Anti-Oxidant and Hepatoprotective activity of Desmostachya bipinnata Leaf Extracts by Various Hepatotoxin Induced Albino Rat Models
Authors
1 Department of Pharmacology, RVS college of Pharmaceutical Sciences, Sulur, Coimbatore, IS
2 Department of Pharmacology, RVS college of Pharmaceutical Sciences, Sulur, Coimbatore, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 8, No 3 (2016), Pagination: 109-115Abstract
Liver diseases are the major medical problems faced by the people all over the world. About 20,000 deaths occur every year due to liver disorders Liver diseases are mainly caused by toxic chemicals, excessive intake of alcohol, infections and autoimmune disorders. Hepatotoxicity mainly implies chemical-driven liver damage. Certain drugs when taken in overdose and sometimes even when administered within therapeutic ranges may injure many organs. Some chemical agents including those that are used in laboratories (CCl4, paracetamol) and industries (Lead, arsenic) and natural chemicals (microcystine, aflatoxins) and herbal remedies (Cascara sagrada, Ephedra) can also cause hepatotoxicity Chemicals which cause liver injury are collectively known as hepatotoxins.
So the aim of this research is to evaluate anti- oxidant and hepatoprotective activity using Desmostachya bipinnata leaf extract because very less pharmacological studies have been carried out on the leaf of Desmostachya bipinnata by emphasizing on the antioxidant and hepatoprotective activity in Swiss albino rat model.
The whole plant materials are useful for the symptoms of different diseases. Desmostachya bippinata is indicated by several medicinal treatments for jaundice and other gastro intestinal disorder, Plant is a common weed plant mainly cultivated Northern parts of India.
Keywords
Hepatoprotective, Anti oxidant, Desmostachya bipinnata.- Anti Diabetic Activity and Toxicity Study of Petroleum Ether Extracts of Ixora coccinea Flower in Streptozotocin Induced Diabetic in Albino Rat Model
Authors
1 Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 8, No 3 (2016), Pagination: 97-105Abstract
Diabetic millets often referred to simply as diabetes (Ancient Greek: diabetes" to pass through [urine]") is a syndrome of disorder metabolism, usually due to a combination of hereditary and environment causes, resulting in abnormally high blood sugar level (hyperglycemia).Diabetes is described as starvation in the midst of plenty. Because the body will have high amount of glucose level but the cells are incapable of consume it because of osmotic difference Insulin is a hormone produced in the pancreas, which enable body cells to absorb glucose, to turn into energy. If the body cells cannot absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to acute metabolic complications including keto acidosis and in the long term contribute to chronic micro-vascular complications.
Ixora coccinea is a low-growing tropical shrub notable for its bright coloured flowers which are composed of many small blooms massed together into dense, flat-topped flower heads. Ixora coccinea is one of the few Ixora species that make good indoor plants along with several kinds developed from it. It is primarily ornamental plant. Cut specimens are long lasting and are often used in floral arrangements. It is sometimes used as a hedge. In tropical Asia the flowers, bark and leaves of this plant are used in traditional medicine.